eRAM
encyclopedia of Rare Disease Annotation for Precision Medicine
| Disease | li-fraumeni syndrome |
| Comorbidity | C0011847|diabetes |
| Sentences | 2 |
| PubMedID- 21283750 | Applying an additive genetic model the minor diabetes-associated g-allele of the tp53 rs1042522 showed nominal association with higher levels of fasting plasma glucose (p = 0.03) (table 2). |
| PubMedID- 21146886 | We demonstrated that the polymorphism in tp53 (rs1042522) was associated with type 2 diabetes, and that potential interaction of tp53 (rs1042522) and rapgef1 (rs11243444), or nrf1 (rs1882095) increased the risk of type 2 diabetes. |
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